INFORMATION
The IDKmonitor Ustekinumab Free Anti-drug Antibody ELISA measures free antibodies against ustekinumab (e.g. STELARA®). This assay enables the reliable determination of free, unbound anti-drug antibodies; therefore it is ideal for therapy monitoring when a measurable ustekinumab concentration is not expected, or the unbound fraction of anti-drug antibodies is required, for example shortly before the next infusion. In combination with the drug level determination, the IDKmonitor® Ustekinumab Free Anti-drug Antibody ELISA supports the monitoring and optimisation of therapy.
KEY ADVANTAGES
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Supports the investigation of primary non-response and loss of response to ustekinumab
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Highly sensitive assay that detects free anti-ustekinumab antibodies (those unbound to ustekinumab)
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May help to predict long term outcome of disease
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Applicable to both gastroenterology and rheumatology
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Automatable on ELISA automates (e.g. Dynex D2)
