INFORMATION
GastroPanel® is a simple blood test for Primary Care that aids the diagnosis of dyspepsia. It is used to effectively rule out diseases of the gastric mucosa characterised by Helicobacter pylori (H.pylori) infection and atrophic gastritis. Based on the results, functional dyspepsia can be differentiated from organic dyspepsia in patients presenting to their GP so patients can be managed accordingly. The results also give important information on possible risks related to H. pylori infection, atrophic gastritis and high acid production.
H. pylori infection is diagnosed by an antibody test which is combined with Pepsinogen I, Pepsinogen II and Gastrin-17 analysis to describe the structure and function of the whole gastric mucosa. Atrophic Gastritis – a precancerous condition of the gastric mucosa – is identified by GastoPanel® without the need for, or prior to endoscopy. The more severe is the atrophic gastritis in the corpus mucosa, the lower the level of Pepsinogen I, and the ratio of pepsinogenI/II in blood.
The more severe the atrophic gastritis of antrum mucosa, the lower the the level of Gastrin-17 in blood.
GastroPanel® gives a reliable diagnosis of:
Healthy stomach mucosa. When the stomach mucosa is healthy, the cause of stomach symptoms is most likely to be functional dyspepsia or disease outside the stomach.
Acid dysregulation
H. pylori infection
Atrophic gastritis (severely damaged and dysfunctional stomach mucosa) and specifically the location of the disease, e.g. corpus, antrum, or both mucosa
GastroPanel® consists of four ELISAs and can be set up in any local laboratory or can be requested via BIOHIT’s Service Laboratory.
FEATURES
Four highly specific 96-well ELISA assays with harmonised protocols:
Pepsinogen I
Pepsinogen II
Amidated Gastrin-17
Helicobacter pylori IgG
Test up to 45 samples per batch
Easily automated on ELISA automates (e.g. Dynex DS2)
Excellent predictive value for the diagnosis of Atrophic Gastritis (compared to histology)
See individual GastroPanel assays for more details
Test also available as a service from BIOHIT Service Laboratory
BENEFITS
Simple non-invasive blood test for Primary Care and Screening settings
Harmonised laboratory protocols for concomitant testing and rapid throughput
Obtain clinically relevant information about the stomach mucosa
Make recommendations for patient management and referral
Target endoscopy resources towards those at greatest risk
Identify patients at risk of diseases characterised by Atrophic Gastritis:
Gastric Cancer
Intestinal Metaplasia
Acid dysregulation
Vitamin and micronutrient deficiency
